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#metabolicSyndrome

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The harmful role of sugars in the diet, opinion EFSA

Consumption of sugars adversely affects health and should be minimized. This was stated by the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) of EFSA in the scientific opinion published on 28.2.22. (1) …
#dining #cooking #diet #food #Italiandiet #addedsugars #EFSA #Italia #Italian #ItalianDiet #italiano #italy #metabolicsyndrome #Sugar
diningandcooking.com/2269335/t

'Effect of the Variant rs7903146 of Transcription Factor 7-Like 2 Gene on Anthropometric and Metabolic Responses to a 24 Weeks Meal Replacement Hypocaloric Diet' - an article in Karger: Nutrition and Dietetics on #ScienceOpen:

🔗 scienceopen.com/document?vid=a

ScienceOpenEffect of the Variant rs7903146 of Transcription Factor 7-Like 2 Gene on Anthropometric and Metabolic Responses to a 24 Weeks Meal Replacement Hypocaloric Diet<p xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" dir="auto" id="d6618e132"> <b> <i>Introduction:</i> </b> Some studies have demonstrated the effect of the rs7903146 genetic variant on weight response after different dietary strategies. The objective of our study was to evaluate the role of this genetic variant of the <i>TCF7L2</i> gene on weight loss and diabetes mellitus progression following a partial meal replacement (pMR) hypocaloric diet. <b> <i>Methods:</i> </b> We conducted an interventional study in 214 subjects with obesity and a body mass index (BMI) >35 kg/m <sup>2</sup>. The subjects received two servings per day of a normocaloric hyperproteic formula for 24 weeks as part of a pMR diet. Body weight, BMI, fat mass, waist circumference, lipid profile, fasting insulin levels, and HOMA-IR were determined. All patients were genotyped for rs7903146 and evaluated under a dominant model (CC vs. CT + TT). <b> <i>Results:</i> </b> The decrease at 24 weeks was higher in non-T-allele carriers compared to T-allele carriers (BMI: −3.3 ± 0.3 kg/m <sup>2</sup> vs. −2.2 ± 0.2 kg/m <sup>2</sup>; <i>p</i> = 0.02; weight: −9.5 ± 1.1 kg vs. −5.0 ± 1.0 kg; <i>p</i> = 0.01; fat mass: −8.7 ± 0.2 kg vs. −4.0 ± 0.2 kg; <i>p</i> = 0.04; waist circumference: −8.0 ± 0.2 cm vs. −3.0 ± 0.4 cm; <i>p</i> = 0.04; glucose levels: −7.1 ± 1.2 mg/dL vs. −1.2 ± 1.1 mg/dL; <i>p</i> = 0.01; insulin: −10.1 ± 1.1 µIU/L vs. −4.0 ± 1.0 µIU/L; <i>p</i> = 0.01; HOMA-IR: −2.1 ± 1.1 units vs. −0.5 ± 0.1 units; <i>p</i> = 0.01; C-reactive protein: −0.9 ± 0.1 mg/dL vs. −0.4 ± 0.2 mg/dL; <i>p</i> = 0.01; triglycerides: −17.1 ± 0.1 mg/dL vs. −9.1 ± 0.2 mg/dL; <i>p</i> = 0.01; and HbA1c: −1 ± 0.1% vs. −0.3 ± 0.2%; <i>p</i> = 0.01). Following the dietary intervention, only non-T-allele carriers showed a significant decrease in the frequency of hypertriglyceridemia, abdominal waist, hyperglycemia, and DM2. <b> <i>Conclusions:</i> </b> The <i>TCF7L2</i> (rs7903146) polymorphism modulates pMR diet-induced changes in body weight, lipid metabolism, and insulin resistance. These changes lead to a significant decrease in the prevalence of hyperglycemia and other components of metabolic syndrome. </p>

Low-gluten diets disrupt gut health by depleting key bacteria

Scientists uncover how long-term gluten reduction, often seen as a health boost, can actually upset gut balance, strip…
#NewsBeep #News #US #USA #UnitedStates #UnitedStatesOfAmerica #Nutrition #Ataxia #Bacteria #Bacterial #CeliacDisease #Clostridia #Diet #digestion #Ethanol #Gluten #Health #inflammation #MetabolicSyndrome #Metabolites #Nutrients #Peptides #Syndrome #Wheat
newsbeep.com/us/38454/

A study of over 11,000 people from a population with a base rate of ~32% for the prevalence of metabolic syndrome found that serum concentrations of vitamin D and D3, but not D2, were inversely correlated with metabolic syndrome in adults aged 60 or older, but not in adults aged 45-59.

nutritionandmetabolism.biomedc

BioMed CentralPrevalence of metabolic syndrome with different serum vitamin D levels in middle-aged and older adults - Nutrition & MetabolismBackground The relationship between serum vitamin D levels and metabolic syndrome (MetS) has been controversial. This study focused on the relationship between the prevalence of MetS and serum vitamin D levels in middle-aged and elderly people. Methods This study included middle-aged and older adults who participated in the 2023 Zhejiang Provincial Nutrition and Health Survey, which was conducted in 90 districts and counties in Zhejiang Province, China. Results A total of 11,305 participants were included in this study. MetS was prevalent in 31.7% of participants. Vitamin D and vitamin D3 concentrations were inversely associated with MetS prevalence (Ptrend<0.05), but not with vitamin D2, regardless of whether logistic regression models were adjusted for confounding factors. After adjusting for age, sex, physical activity level, smoking status, education level, annual per capita household income, and body mass index residuals, the highest tertile (Q3) of vitamin D (odds ratio [OR], 0.779; 95% confidence interval [CI], 0.702–0.865) and vitamin D3 (OR, 0.787; 95% CI, 0.709–0.875) concentrations had a lower risk of MetS than the lowest tertile (Q1). We found that vitamin D and D3 levels were correlated with age (Pinteraction<0.05). When age-stratified analyses were performed, vitamin D and vitamin D3 levels were significantly negatively associated with MetS in older adults but not in middle-aged adults. Conclusions Low total serum vitamin D and vitamin D3 levels were associated with a higher risk of MetS in adults aged 60 years and older.
Continued thread

5/7
Let us also consider ALA’s influence on metabolism, particularly its effect on improving insulin sensitivity as noted by research in the 'Diabetes Technology & Therapeutics' (2018). Such advancements underscore the need for integrative approaches combining diet, exercise, and appropriate supplementation for metabolic health. #MetabolicSyndrome #HealthAndWellness

Continued thread

Let us also consider ALA’s influence on metabolism, particularly its effect on improving insulin sensitivity as noted by research in the 'Diabetes Technology & Therapeutics' (2018). Such advancements underscore the need for integrative approaches combining diet, exercise, and appropriate supplementation for metabolic health. #MetabolicSyndrome #HealthAndWellness

Continued thread

5/7
Let us also consider ALA’s influence on metabolism, particularly its effect on improving insulin sensitivity as noted by research in the 'Diabetes Technology & Therapeutics' (2018). Such advancements underscore the need for integrative approaches combining diet, exercise, and appropriate supplementation for metabolic health. #MetabolicSyndrome #HealthAndWellness

#LandBack at #Barnhart:
Contextualizing the Re-occupation of #BarnhartIsland in Shared Legacies of Struggle

From #TurtleIsland to #Palestine, the struggle at #Akwesasne is rooted in the shared struggle of all #OppressedPeoples of the world who are opposing the illogic of #SettlerCapitalism and the endless violation of the #lands and #waters that our current economic system necessitates.

By Jennifer Lee
June 25, 2024

"On May 21, 2024, a group of eight Kanien’kehá:ka (#Mohawk) community members from Akwesasne were arrested at Niionenhiasekowa:ne (Barnhart Island). Certain individuals among the '#Akwesasne8' had originally gone to Barnhart to exercise their right to build a hunting and gathering shelter on their own territory, in part to protest an ongoing land claim settlement that threatens to hand over Kanien’kehá:ka title to this island, among other traditionally held territories, to New York State. The settlement is being negotiated between New York entities and three Akwesasne government councils.

"Presently, the settlement negotiations would require the extinguishment of Mohawk title to Barnhart Island, which would be effectuated through an act of Congress. By asserting their right to the land, the #Akwesasne8 have sent a clear message to both negotiating parties. Barnhart Island, like all other territories illegally stolen and swindled from their community, is not for sale—particularly not by collaborationist band and tribal council entities that purport to represent the full community but that were in fact historically imposed upon it at gunpoint.

"The fact that a group of eight community members was surrounded within just a few hours by approximately 35 police agents (including both border patrol agents and state troopers) is a clear indication of the strategic significance of this island to the interests of settler-capital. As Taiewennahawi (Marina Johnson-Zafiris), one of the eight arrestees, explains in her article 'Akwesasne and the History of #Hydropower,' the Moses-Saunders #hydrodam, located at the east end of Barnhart Island, is one of the many dams along the St. Lawrence Seaway that has supplied 'cheap' electricity to an unending procession of heavily #polluting factories since the 1950s.

"For decades, dirty plants like #Alcoa, #GeneralMotors, and #ReynoldsMetals harnessed the immense power of the #Kaniatarowanenneh (#SaintLawrenceRiver) at the Moses-Saunders dam to manufacture aluminum, a cheap, abundant, and malleable building material that requires vast amounts of power to extract and process. Not only was hydropower-fueled aluminum production critical to New York’s economic development, it was central to the national pride and independence of so-called #Québec. Eager to assert its autonomy from Anglophone capital in the 1960s, the province began damming rivers on #Indigenous land in a frenzy of hydropower nationalism.

"Upstream on the St. Lawrence, the aluminum plants at Akwesasne used a #toxic #sludge containing polychlorinated biphenyls (#PCBs) as a hydraulic fluid during the production process. These PCBs were manufactured by the infamously litigious #corporation #Monsanto, which continues to evade public #accountability for discharging this known #carcinogen into the St. Lawrence River and onto Kanien’kehá:ka soil. The #carcinogenic soup was left exposed on the very grounds where the children of Akwesasne played and where families grew their vegetables. Today, Akwesasne sits downstream and downwind of three heavily #polluted #superfund sites, and residents of Akwesasne report that almost everyone they know has a friend or family member suffering from a rare #cancer, #MetabolicSyndrome, or #autoimmune disorder. Rare, life-threatening illnesses exist at Akwesasne at rates that the public would never consider normal or acceptable in any non-Indigenous community.

"Dana-Leigh Thompson, one of the Akwesasne 8, lived about 3,000 feet from the PCB #dumpsite of the #GeneralMotors (#GM) factory for a decade. She calls what is happening to the community nothing short of an '#environmental #genocide.'"

Read more:

magazine.scienceforthepeople.o

Science for the People Magazine · Land Back at Barnhart • SftP MagazineThe “Akwesasne 8,” arrested exercising their rights to the land, brings to fore the interconnectedness of the world's anticolonial struggles.
Continued thread

5/7
Let us also consider ALA’s influence on metabolism, particularly its effect on improving insulin sensitivity as noted by research in the 'Diabetes Technology & Therapeutics' (2018). Such advancements underscore the need for integrative approaches combining diet, exercise, and appropriate supplementation for metabolic health. #MetabolicSyndrome #HealthAndWellness

Nuevo índice/#biomarcador de #RiesgoCardiovascular en pacientes con #SíndromeMetabólico.

El #TyG (índice Triglicéridos y Glucosa) menor a 9 tiene un valor predictivo negativo de 89% para riesgo intermedio/alto de eventos cardiovasculares en los siguientes 10 años.

Y es relativamente barato y fácil de aplicar.

#Biomarker #MetabolicSyndrome #PreDiabetes #CardiovascularRisk #Health

pubmed.ncbi.nlm.nih.gov/361611

PubMedTriglyceride glucose index: A new biomarker in predicting cardiovascular risk - PubMedThe TyG index showed a good predictive capacity for cardiovascular risk in ten years assessed by the FRS.