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ChemistryViewsTotal Synthesis of Ukabamide, a Drug Candidate against Sleeping Sickness: Lipopeptide from marine cyanobacteria could lead to new antitrypanosomal drugs <a href="https://www.chemistryviews.org/total-synthesis-of-ukabamide-a-drug-candidate-against-sleeping-sickness/" target="_blank" rel="nofollow noopener" translate="no">https://www.chemistryviews.org/total-synthesis-of-ukabamide-a-drug-candidate-against-sleeping-sickness/</a><a href="https://mstdn.social/tags/marinelipopeptide" class="mention hashtag" rel="tag">#marinelipopeptide</a> <a href="https://mstdn.social/tags/sleepingsickness" class="mention hashtag" rel="tag">#sleepingsickness</a> <a href="https://mstdn.social/tags/antitrypanosomal" class="mention hashtag" rel="tag">#antitrypanosomal</a> <a href="https://mstdn.social/tags/drugdevelopment" class="mention hashtag" rel="tag">#drugdevelopment</a> <a href="https://mstdn.social/tags/chemistry" class="mention hashtag" rel="tag">#chemistry</a> <a href="https://mstdn.social/tags/chemistryviews" class="mention hashtag" rel="tag">#chemistryviews</a> <a href="https://mstdn.social/tags/chemviews" class="mention hashtag" rel="tag">#chemviews</a>

Punk Metal n Bowie<a href="https://kolektiva.social/tags/Geneticmutations" class="mention hashtag" rel="nofollow noopener" target="_blank">#Geneticmutations</a> in <a href="https://kolektiva.social/tags/parasites" class="mention hashtag" rel="nofollow noopener" target="_blank">#parasites</a> may lead to <a href="https://kolektiva.social/tags/globalspread" class="mention hashtag" rel="nofollow noopener" target="_blank">#globalspread</a> of <a href="https://kolektiva.social/tags/sleepingsickness" class="mention hashtag" rel="nofollow noopener" target="_blank">#sleepingsickness</a> <a href="https://phys.org/news/2024-12-genetic-mutations-parasites-global-sickness.html" rel="nofollow noopener" translate="no" target="_blank">https://phys.org/news/2024-12-genetic-mutations-parasites-global-sickness.html</a>

Lukas VFN 🇪🇺The prospect of a better treatment for Chagas disease and sleeping sickness <a href="https://blogs.biomedcentral.com/bugbitten/2023/07/21/the-prospect-of-a-better-treatment-for-chagas-disease-and-human-african-sleeping-sickness/" rel="nofollow noopener" target="_blank">https://blogs.biomedcentral.com/bugbitten/2023/07/21/the-prospect-of-a-better-treatment-for-chagas-disease-and-human-african-sleeping-sickness/</a><a href="https://scholar.social/tags/Cyanotriazoles" class="mention hashtag" rel="nofollow noopener" target="_blank">#Cyanotriazoles</a> are selective topoisomerase II poisons that rapidly cure trypanosome infections <a href="https://www.science.org/doi/10.1126/science.adh0614" rel="nofollow noopener" target="_blank">https://www.science.org/doi/10.1126/science.adh0614</a>"<a href="https://scholar.social/tags/NeglectedTropicalDiseases" class="mention hashtag" rel="nofollow noopener" target="_blank">#NeglectedTropicalDiseases</a> caused by <a href="https://scholar.social/tags/SingleCelled" class="mention hashtag" rel="nofollow noopener" target="_blank">#SingleCelled</a> <a href="https://scholar.social/tags/parasites" class="mention hashtag" rel="nofollow noopener" target="_blank">#parasites</a> (<a href="https://scholar.social/tags/trypanosomatids" class="mention hashtag" rel="nofollow noopener" target="_blank">#trypanosomatids</a>) include <a href="https://scholar.social/tags/ChagasDisease" class="mention hashtag" rel="nofollow noopener" target="_blank">#ChagasDisease</a>, <a href="https://scholar.social/tags/SleepingSickness" class="mention hashtag" rel="nofollow noopener" target="_blank">#SleepingSickness</a> & <a href="https://scholar.social/tags/leishmaniasis" class="mention hashtag" rel="nofollow noopener" target="_blank">#leishmaniasis</a>. Progress in treatment of these <a href="https://scholar.social/tags/diseases" class="mention hashtag" rel="nofollow noopener" target="_blank">#diseases</a> had been slow, though large chemical library screens are now showing promising results."

DNDiExciting news for <a href="https://mas.to/tags/sleepingsickness" class="mention hashtag" rel="nofollow noopener" target="_blank">#sleepingsickness</a>: acoziborole, an oral, single-dose treatment developed by <a href="https://mas.to/@dndi" class="u-url mention" rel="nofollow noopener" target="_blank">@dndi</a> & its partners was shown to be safe & effective with treatment success rates of up to 95%, in a paper published by <a href="https://med-mastodon.com/@thelancet" class="u-url mention" rel="nofollow noopener" target="_blank">@thelancet</a>. The disease ‘could become the first disease that is eradicated thanks to a drug rather than a vaccine,’ wrote independent expert Jacques Pépin in a Comment. <a href="https://www.telegraph.co.uk/global-health/science-and-disease/new-cure-sleeping-sickness-could-eliminate-nightmare-disease/" rel="nofollow noopener" target="_blank">https://www.telegraph.co.uk/global-health/science-and-disease/new-cure-sleeping-sickness-could-eliminate-nightmare-disease/</a>

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