New subtack
#foxes #complexsystems #domesticationsyndrome #neuralcrest

https://open.substack.com/pub/sterlinga/p/foxes?r=1smcrn&utm_campaign=post&utm_medium=web&showWelcomeOnShare=true

Intercellular communication is crucial for formation of the #TrigeminalGanglion. @PstroblM &co reveal that miR-203 is secreted by #NeuralCrest cells in #ExtracellularVesicles and taken up by #placode cells, regulating their condensation #PLOSBiology https://plos.io/3Lxz5sy

#Cilia are essential for early embryonic L-R patterning, but what about later? Tissue/time-specific cilia inhibition in mouse embryos reveals a cell-autonomous role for cilia in #NeuralCrest-mediated #craniofacial & body wall closure defects #PLOSBiology https://plos.io/3NqvcHn

#Cohesinopathy

BRD4 (acetyl lysine reader)-NIPBL (cohesin loading ) complex is critical to #NeuralCrest differentiation into #SmoothMuscleCell

BRD4 depletion->#GenomeFolding+loop extrusion

BRD4 in #AorticAneurysm?

Dr. Rajan Jain lab Nature Genet 2021
https://www.nature.com/articles/s41588-021-00934-8

Check it out (and please boost this)!

We are recruiting two full time researchers to study #lipids in #neuralcrest #devbiol! Interested in joining us as we build an engaging, welcoming, and inclusive group at Johns Hopkins? Apply now!

Research Technologist (https://jobs.jhu.edu/job/Baltimore-Research-Technologist-MD-21205/973265800/)
Research Specialist (https://jobs.jhu.edu/job/Baltimore-Research-Specialist-MD-21205/972877200/)

Alas, a very windy and wet day in Halifax, Nova Scotia today. Perfect for doing whole mount embryo immunostaining experiments, organoid differentiation assays, and correcting term papers. Also reviewing, meeting guest lecturers, meetings…all the things we do at the university! #neurobiology #developmentalbiology #DevBio #cytoskeleton #neuralcrest

Latest work from our lab examining the interface between tumour initiation and embryonic cell fate decisions: a great collaboration with Florian Halbritter, spearheaded by Ingrid Saldana-Guerrero and Luis Montano-Gutierrez (all Mastodon-less, I think) #devbiol #Devbiol #stemcell #cancer #neuroblastoma #neuralcrest
https://www.biorxiv.org/content/10.1101/2022.11.21.515753v1