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Daniel Caron<p>Human aging is assoc. with inflammation and intestinal barrier dysfunction. One might assume that barrier permeability would spark increased inflammation. This (and prev.) work suggests the opposite—that <a href="https://genomic.social/tags/inflammaging" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>inflammaging</span></a>, driven by <a href="https://genomic.social/tags/monocytes" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>monocytes</span></a> and <a href="https://genomic.social/tags/macrophages" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>macrophages</span></a> appear to *cause* the barrier dysfunction!</p>
Erin<p>Question to anyone familar with <a href="https://mstdn.social/tags/TransHealthcare" class="mention hashtag" rel="tag">#<span>TransHealthcare</span></a> <a href="https://mstdn.social/tags/Hematology" class="mention hashtag" rel="tag">#<span>Hematology</span></a> </p><p>Is there a relationship between elevated <a href="https://mstdn.social/tags/WBC" class="mention hashtag" rel="tag">#<span>WBC</span></a> (<a href="https://mstdn.social/tags/neutrophils" class="mention hashtag" rel="tag">#<span>neutrophils</span></a>, <a href="https://mstdn.social/tags/lymphocytes" class="mention hashtag" rel="tag">#<span>lymphocytes</span></a>, <a href="https://mstdn.social/tags/monocytes" class="mention hashtag" rel="tag">#<span>monocytes</span></a>) &amp; <a href="https://mstdn.social/tags/Platelets" class="mention hashtag" rel="tag">#<span>Platelets</span></a>, decreased <a href="https://mstdn.social/tags/RBC" class="mention hashtag" rel="tag">#<span>RBC</span></a>, <a href="https://mstdn.social/tags/Hemocrit" class="mention hashtag" rel="tag">#<span>Hemocrit</span></a>, <a href="https://mstdn.social/tags/Anemia" class="mention hashtag" rel="tag">#<span>Anemia</span></a>, <a href="https://mstdn.social/tags/Hgb" class="mention hashtag" rel="tag">#<span>Hgb</span></a>, <a href="https://mstdn.social/tags/mpv" class="mention hashtag" rel="tag">#<span>mpv</span></a> and <a href="https://mstdn.social/tags/HRT" class="mention hashtag" rel="tag">#<span>HRT</span></a> for male to female <a href="https://mstdn.social/tags/transgender" class="mention hashtag" rel="tag">#<span>transgender</span></a> individuals with no other evidence of blood disease, infection or <a href="https://mstdn.social/tags/cancer" class="mention hashtag" rel="tag">#<span>cancer</span></a>? </p><p><a href="https://mstdn.social/tags/CTScans" class="mention hashtag" rel="tag">#<span>CTScans</span></a> are clean, <a href="https://mstdn.social/tags/BoneMarrowBiopsy" class="mention hashtag" rel="tag">#<span>BoneMarrowBiopsy</span></a> clean. Doc wants to repeat however.</p>
Giuseppe Michieli<p>Infiltrating <a href="https://mstdn.science/tags/monocytes" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>monocytes</span></a> drive <a href="https://mstdn.science/tags/cardiac" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>cardiac</span></a> <a href="https://mstdn.science/tags/dysfunction" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>dysfunction</span></a> in a <a href="https://mstdn.science/tags/cardiomyocyte" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>cardiomyocyte</span></a>-restricted mouse model of <a href="https://mstdn.science/tags/SARS" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>SARS</span></a>-CoV-2 infection, J Virol.: <a href="https://journals.asm.org/doi/full/10.1128/jvi.01179-24?af=R" rel="nofollow noopener noreferrer" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">journals.asm.org/doi/full/10.1</span><span class="invisible">128/jvi.01179-24?af=R</span></a> </p><p>These findings establish a mouse <a href="https://mstdn.science/tags/model" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>model</span></a> of SARS-CoV-2 cardiomyocyte infection that recapitulates features of cardiac dysfunctions of COVID-19 and suggests that both viral replication and resultant innate immune responses contribute to cardiac pathology.</p>
FranklinLab<p>13/ 🔗 Read the full paper here: <a href="https://www.embopress.org/doi/full/10.1038/s44321-024-00093-3" rel="nofollow noopener noreferrer" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">embopress.org/doi/full/10.1038</span><span class="invisible">/s44321-024-00093-3</span></a></p><p><a href="https://mastodon.social/tags/Immunology" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Immunology</span></a> <a href="https://mastodon.social/tags/Research" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Research</span></a> <a href="https://mastodon.social/tags/Platelets" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Platelets</span></a> <a href="https://mastodon.social/tags/Monocytes" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Monocytes</span></a> <a href="https://mastodon.social/tags/Inflammation" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Inflammation</span></a> <a href="https://mastodon.social/tags/EMBO" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>EMBO</span></a> <a href="https://mastodon.social/tags/Science" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Science</span></a> <a href="https://mastodon.social/tags/MedicalResearch" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>MedicalResearch</span></a></p>
Arjan Boltjes<p>" The insights derived from this analysis do not only support a CD19 CAR T cell-mediated reset of the memory B cell compartment, but also the parallel inhibition of the interferon signature<br>in <a href="https://mastodon.social/tags/monocytes" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>monocytes</span></a> and <a href="https://mastodon.social/tags/Tcells" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Tcells</span></a> of <a href="https://mastodon.social/tags/SLE" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>SLE</span></a> patients"</p><p><a href="https://insight.jci.org/articles/view/179433" rel="nofollow noopener noreferrer" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">insight.jci.org/articles/view/</span><span class="invisible">179433</span></a></p><p>Striking that this apparently works better in getting rid of certain memory <a href="https://mastodon.social/tags/Bcells" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Bcells</span></a> than anti-CD20 antibodies.</p><p><a href="https://mastodon.social/tags/scRNAseq" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>scRNAseq</span></a> <a href="https://mastodon.social/tags/TCR" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>TCR</span></a> <a href="https://mastodon.social/tags/carTcells" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>carTcells</span></a> <a href="https://mastodon.social/tags/OpenAccess" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>OpenAccess</span></a> <a href="https://mastodon.social/tags/science" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>science</span></a></p>
The EMBO Journal<p><a href="https://sciencemastodon.com/tags/Hypoxia" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Hypoxia</span></a> activates SREBP2 through Golgi disassembly in bone marrow-derived <a href="https://sciencemastodon.com/tags/monocytes" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>monocytes</span></a> for&nbsp;enhanced tumor growth<br>Tsuyoshi Osawa et al show that low-oxygen conditions induce lineage-specific activation of <a href="https://sciencemastodon.com/tags/SREBP2" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>SREBP2</span></a> via <a href="https://sciencemastodon.com/tags/Golgi" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Golgi</span></a>-ER fusion, promoting lipid biosynthesis, myeloid cell infiltration, and <a href="https://sciencemastodon.com/tags/tumorigenesis" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>tumorigenesis</span></a><br><a href="https://www.embopress.org/doi/full/10.15252/embj.2023114032" rel="nofollow noopener noreferrer" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">embopress.org/doi/full/10.1525</span><span class="invisible">2/embj.2023114032</span></a></p>
Benjamin S-B :verified:<p>Very exciting that this paper is out now in <a href="https://genomic.social/tags/cancercell" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>cancercell</span></a>: <a href="https://www.cell.com/cancer-cell/fulltext/S1535-6108(23)00216-7" rel="nofollow noopener noreferrer" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">cell.com/cancer-cell/fulltext/</span><span class="invisible">S1535-6108(23)00216-7</span></a></p><p>In brief: we show that in esophageal <a href="https://genomic.social/tags/adenocarcinoma" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>adenocarcinoma</span></a> <a href="https://genomic.social/tags/checkpoint" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>checkpoint</span></a> <a href="https://genomic.social/tags/therapy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>therapy</span></a> success is predicted by an independent combination of mutation burden and the amount of <a href="https://genomic.social/tags/monocytes" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>monocytes</span></a> in the tumour pre-treatment (as measured by RNAseq). Very exciting link between <a href="https://genomic.social/tags/myeloid" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>myeloid</span></a> cells and <a href="https://genomic.social/tags/immune" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>immune</span></a> response to <a href="https://genomic.social/tags/cancer" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>cancer</span></a>!</p>
Arjan Boltjes<p>"NB cells signal to the BM microenvironment, rewiring via macrophage migration inhibitory factor and <a href="https://mastodon.social/tags/midkine" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>midkine</span></a> signaling specifically <a href="https://mastodon.social/tags/monocytes" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>monocytes</span></a> ..."</p><p><a href="https://mastodon.social/tags/Neuroblastoma" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Neuroblastoma</span></a> paper by Fetahu et al., the latest publication from the Taschner-Mandl lab in Vienna.</p><p>Going through this right now - very alike our own work - and talking to a few team members on Wednesday while they visit our center.</p><p><a href="https://mastodon.social/tags/macrophages" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>macrophages</span></a> <a href="https://mastodon.social/tags/scATACseq" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>scATACseq</span></a> <a href="https://mastodon.social/tags/scRNAseq" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>scRNAseq</span></a> <a href="https://mastodon.social/tags/OpenAccess" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>OpenAccess</span></a> <a href="https://mastodon.social/tags/cancer" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>cancer</span></a> <a href="https://mastodon.social/tags/immunology" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>immunology</span></a> </p><p>Data available on EGA, behind a DAC.</p>
Steve Dustcircle 🌹<p><a href="https://masto.ai/tags/Monocytes" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Monocytes</span></a> and the neurological health of <a href="https://masto.ai/tags/LongCovid" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>LongCovid</span></a> Patients<br><a href="https://boingboing.net/2023/05/10/monocytes-and-the-neurological-health-of-long-covid-patients.html" rel="nofollow noopener noreferrer" target="_blank"><span class="invisible">https://</span><span class="ellipsis">boingboing.net/2023/05/10/mono</span><span class="invisible">cytes-and-the-neurological-health-of-long-covid-patients.html</span></a><br><a href="https://www.scientificamerican.com/article/long-covid-now-looks-like-a-neurological-disease-helping-doctors-to-focus-treatments/" rel="nofollow noopener noreferrer" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">scientificamerican.com/article</span><span class="invisible">/long-covid-now-looks-like-a-neurological-disease-helping-doctors-to-focus-treatments/</span></a></p>
Bene<p><span class="h-card"><a href="https://det.social/@LangzeitC" class="u-url mention" rel="nofollow noopener noreferrer" target="_blank">@<span>LangzeitC</span></a></span> This article is a perfect example of why <a href="https://scholar.social/tags/covid" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>covid</span></a> media coverage is part of the problem. </p><p>Article:<br>197! differences in the <a href="https://scholar.social/tags/epigenetics" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>epigenetics</span></a> of <a href="https://scholar.social/tags/monocytes" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>monocytes</span></a> from <a href="https://scholar.social/tags/LongCovid" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>LongCovid</span></a> patients! Whoot? 😱😱😱</p><p>Reading the actual paper, which can be found here:<br><a href="https://clinicalepigeneticsjournal.biomedcentral.com/articles/10.1186/s13148-022-01398-1#MOESM1" rel="nofollow noopener noreferrer" target="_blank"><span class="invisible">https://</span><span class="ellipsis">clinicalepigeneticsjournal.bio</span><span class="invisible">medcentral.com/articles/10.1186/s13148-022-01398-1#MOESM1</span></a></p><p>you will find it is based on 10(!) patients and that there is an arbitrarily chosen difference of <a href="https://scholar.social/tags/methylation" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>methylation</span></a> of 0.2 that leads to that number of 197. What that means? Who knows? But its enough to ventilate it..</p>
Ingo Fricke<p><a href="https://sciencemastodon.com/tags/Innate" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Innate</span></a> and <a href="https://sciencemastodon.com/tags/Adaptive" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Adaptive</span></a> <a href="https://sciencemastodon.com/tags/Immunity" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Immunity</span></a> during SARS-CoV-2 Infection: Biomolecular Cellular Markers and Mechanisms<br><a href="https://sciencemastodon.com/tags/COVID19" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>COVID19</span></a> <a href="https://sciencemastodon.com/tags/Bcells" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Bcells</span></a> <a href="https://sciencemastodon.com/tags/neutrophils" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>neutrophils</span></a> <a href="https://sciencemastodon.com/tags/dendritic_cells" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>dendritic_cells</span></a> <a href="https://sciencemastodon.com/tags/Tcells" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Tcells</span></a> <a href="https://sciencemastodon.com/tags/NKcells" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>NKcells</span></a> <a href="https://sciencemastodon.com/tags/monocytes" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>monocytes</span></a> <a href="https://sciencemastodon.com/tags/macrophages" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>macrophages</span></a> <a href="https://sciencemastodon.com/tags/SARSCoV2" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>SARSCoV2</span></a><br><a href="https://www.mdpi.com/2076-393X/11/2/408" rel="nofollow noopener noreferrer" target="_blank"><span class="invisible">https://www.</span><span class="">mdpi.com/2076-393X/11/2/408</span><span class="invisible"></span></a></p>
Arjan Boltjes<p>The paper focuses on <a href="https://mastodon.social/tags/DendriticCells" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>DendriticCells</span></a> (DC) and <a href="https://mastodon.social/tags/monocytes" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>monocytes</span></a> from a local inflammatory site, in this case synovial fluid from swollen joints of mainly juvenile <a href="https://mastodon.social/tags/arthritis" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>arthritis</span></a> patients.<br>Very short: one type of DC were very much enriched but seemed relatively quiescent despite the inflammatory surroundings, while other DC and monocytes behaved clearly pro-inflammatory.</p>
Arjan Boltjes<p>Last week, the paper based on my work in the Wilhelmina Children's Hospital (WKZ) was published, with the title "Conventional dendritic cells type 1 are strongly enriched, quiescent and relatively tolerogenic in local inflammatory arthritis".<br><a href="https://doi.org/10.3389/fimmu.2022.1101999" rel="nofollow noopener noreferrer" target="_blank"><span class="invisible">https://</span><span class="ellipsis">doi.org/10.3389/fimmu.2022.110</span><span class="invisible">1999</span></a></p><p>Credits to Anoushka Samat for taking care of this after I left the department. Without her this work would not be out there. And of course thanks to the rest of the team.</p><p><a href="https://mastodon.social/tags/immunology" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>immunology</span></a> <a href="https://mastodon.social/tags/RNAseq" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>RNAseq</span></a> <a href="https://mastodon.social/tags/inflammation" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>inflammation</span></a> <a href="https://mastodon.social/tags/DendriticCells" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>DendriticCells</span></a> <a href="https://mastodon.social/tags/monocytes" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>monocytes</span></a></p>
MaksiSanctum he/him<p>Great thread by Dr Gilchrist <span class="h-card"><a href="https://mstdn.science/@jeffgilchrist" class="u-url mention" rel="nofollow noopener noreferrer" target="_blank">@<span>jeffgilchrist</span></a></span></p><p>How COVID actively suppresses and evades your immune system<br>“ how mild and moderate <a href="https://med-mastodon.com/tags/COVID" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>COVID</span></a> infection reprograms white <a href="https://med-mastodon.com/tags/blood" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>blood</span></a> cells (<a href="https://med-mastodon.com/tags/monocytes" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>monocytes</span></a>) to reduce <a href="https://med-mastodon.com/tags/innate" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>innate</span></a> <a href="https://med-mastodon.com/tags/immune" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>immune</span></a> functions and how it evades the mucus layer in our <a href="https://med-mastodon.com/tags/nose" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>nose</span></a>”</p><p><a href="https://pingthread.com/thread/1612066649934290946" rel="nofollow noopener noreferrer" target="_blank"><span class="invisible">https://</span><span class="ellipsis">pingthread.com/thread/16120666</span><span class="invisible">49934290946</span></a></p>
Jeff Gilchrist<p>How COVID actively suppresses and evades your immune system [Part 2]</p><p>Part 2 looks at how mild and moderate <a href="https://mstdn.science/tags/COVID" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>COVID</span></a> infection reprograms white <a href="https://mstdn.science/tags/blood" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>blood</span></a> cells (<a href="https://mstdn.science/tags/monocytes" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>monocytes</span></a>) to reduce <a href="https://mstdn.science/tags/innate" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>innate</span></a> <a href="https://mstdn.science/tags/immune" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>immune</span></a> functions and how it evades the mucus layer in our <a href="https://mstdn.science/tags/nose" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>nose</span></a> 🧵 1/</p><p>The one page web view is also available here: <a href="https://pingthread.com/thread/1612066649934290946" rel="nofollow noopener noreferrer" target="_blank"><span class="invisible">https://</span><span class="ellipsis">pingthread.com/thread/16120666</span><span class="invisible">49934290946</span></a></p>
Jeff Gilchrist<p>How <a href="https://mstdn.science/tags/COVID" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>COVID</span></a> actively suppresses and evades your <a href="https://mstdn.science/tags/immune" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>immune</span></a> system [Part 1]</p><p>This thread highlights multiple methods that the virus uses to help keep <a href="https://mstdn.science/tags/reinfecting" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>reinfecting</span></a> people including <a href="https://mstdn.science/tags/MHC" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>MHC</span></a>-I and <a href="https://mstdn.science/tags/interferon" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>interferon</span></a> <a href="https://mstdn.science/tags/suppression" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>suppression</span></a>, <a href="https://mstdn.science/tags/evasion" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>evasion</span></a> of Natural Killer (NK) cells, and reprogramming of <a href="https://mstdn.science/tags/monocytes" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>monocytes</span></a>. 🧵 1/</p><p>The one page web view is available here: <a href="https://pingthread.com/thread/1611333222419566594" rel="nofollow noopener noreferrer" target="_blank"><span class="invisible">https://</span><span class="ellipsis">pingthread.com/thread/16113332</span><span class="invisible">22419566594</span></a></p>
Nicole Tan<p>Happy Friday in the lab! Great to be back in the lab all week doing experiments 👩🏻‍🔬 Feeling much less like a hassle and incompetent!<br>I do however feel like I'm spinning a few too many plates at the moment with the masters, exams, applications, clinical work, QIP/portfolio, let alone trying to find time for the classic "New Year New Me" trope... Trying to stay optimistic and realistic! </p><p><a href="https://med-mastodon.com/tags/WomenInScience" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>WomenInScience</span></a> <a href="https://med-mastodon.com/tags/ClinicalResearcher" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>ClinicalResearcher</span></a> <a href="https://med-mastodon.com/tags/MedMastodom" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>MedMastodom</span></a> <a href="https://med-mastodon.com/tags/Blood" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Blood</span></a> <a href="https://med-mastodon.com/tags/Neutrophils" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Neutrophils</span></a> <a href="https://med-mastodon.com/tags/Monocytes" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Monocytes</span></a> <a href="https://med-mastodon.com/tags/laboratorylife" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>laboratorylife</span></a> <a href="https://med-mastodon.com/tags/SelfDoubt" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>SelfDoubt</span></a></p>
Christian Tidona<p>Did you know that during <a href="https://mstdn.science/tags/embryo" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>embryo</span></a> development, migrating <a href="https://mstdn.science/tags/monocytes" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>monocytes</span></a> deposit tracks of pro-angiogenic <a href="https://mstdn.science/tags/migrasomes" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>migrasomes</span></a> guiding the formation of blood vessels?</p><p>In this interesting manuscript published in Nature Cell Biology, researchers at Tsinghua University in Beijing studied this phenomenon in the chorioallantoic membrane of chick embryos: <a href="https://www.nature.com/articles/s41556-022-01026-3" rel="nofollow noopener noreferrer" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">nature.com/articles/s41556-022</span><span class="invisible">-01026-3</span></a></p><p>This could have implications in organotypic <a href="https://mstdn.science/tags/tissueengineering" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>tissueengineering</span></a> and provide new ways how to inhibit <a href="https://mstdn.science/tags/angiogenesis" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>angiogenesis</span></a> in solid <a href="https://mstdn.science/tags/tumors" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>tumors</span></a>.</p>
Claire Adams<p>My first <a href="https://critcare.social/tags/toot" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>toot</span></a> and a <a href="https://critcare.social/tags/introduction" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>introduction</span></a> <br>Currently in my 2nd year of a PhD studying <a href="https://critcare.social/tags/immunometabolism" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>immunometabolism</span></a> in <a href="https://critcare.social/tags/Monocytes" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Monocytes</span></a> and <a href="https://critcare.social/tags/macrophages" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>macrophages</span></a> in <a href="https://critcare.social/tags/Inflammation" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Inflammation</span></a> as a wannabe <a href="https://critcare.social/tags/clinicianscientist" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>clinicianscientist</span></a> Also full-time servant to a mini panther (Oscar) and currently trying to navigate my way around Mastodon! Looking forward to meeting more people here!</p>
haven4books<p><a href="https://weirder.earth/tags/NEISvoid" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>NEISvoid</span></a></p><p>Move Over NK, T and B-cells. Are Monocytes the Real Problem in ME/CFS?</p><p>🔗: <a href="https://www.healthrising.org/blog/2022/11/13/monocytes-real-problem-chronic-fatigue-syndrome/" rel="nofollow noopener noreferrer" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">healthrising.org/blog/2022/11/</span><span class="invisible">13/monocytes-real-problem-chronic-fatigue-syndrome/</span></a></p><p>"Given the strengths of this study – a large, complex study employing ME/CFS patients from ME/CFS experts that used a more effective technique – it has the potential to alter how this disease is viewed immunologically."</p><p><a href="https://weirder.earth/tags/MECFS" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>MECFS</span></a> <a href="https://weirder.earth/tags/pwME" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>pwME</span></a> <a href="https://weirder.earth/tags/immune" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>immune</span></a> <a href="https://weirder.earth/tags/LongCOVID" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>LongCOVID</span></a> <a href="https://weirder.earth/tags/exercise" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>exercise</span></a> <a href="https://weirder.earth/tags/research" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>research</span></a> <a href="https://weirder.earth/tags/TCells" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>TCells</span></a> <a href="https://weirder.earth/tags/macrophages" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>macrophages</span></a> <a href="https://weirder.earth/tags/monocytes" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>monocytes</span></a> <a href="https://weirder.earth/tags/inflammation" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>inflammation</span></a> <a href="https://weirder.earth/tags/NKcells" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>NKcells</span></a> <a href="https://weirder.earth/tags/PEM" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>PEM</span></a> <a href="https://weirder.earth/tags/PESE" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>PESE</span></a> <a href="https://weirder.earth/tags/platelets" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>platelets</span></a> <a href="https://weirder.earth/tags/NIH" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>NIH</span></a> <a href="https://weirder.earth/tags/medstodon" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>medstodon</span></a> </p><p><span class="h-card"><a href="https://a.gup.pe/u/mecfs" class="u-url mention" rel="nofollow noopener noreferrer" target="_blank">@<span>mecfs</span></a></span> <span class="h-card"><a href="https://a.gup.pe/u/longcovid" class="u-url mention" rel="nofollow noopener noreferrer" target="_blank">@<span>longcovid</span></a></span></p>