#Glioblastoma has been a terrible type of cancer, hopefully no longer
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Another experimental anti-tumor therapy based on weaponized immune cells: #macrophages loaded with drugs attack #glioblastoma cells and activate #immune system.
https://www.science.org/doi/10.1126/scitranslmed.adr4058
**Sensitive story**
Last year, early April, I get a call from my dear friend Luke. He says he’s confused. Had a work mtg in front of 75 people. All the sudden couldn’t gather his thoughts, couldn’t speak. Had to leave abruptly. Super embarrassed and concerned, he says to me I think I had a panic attack. We talk about it. Talk to my wife. Few days go by and he gets to the Dr. has an MRI done.
BOOM! His world is rocked! Tells me that he has a large stage 4 aggressive #braincancer #glioblastoma tumor in his head about! 3 days later he has a surgical resection.
That was 13 months ago, 2 resections, 2 chemo and radiation stints, countless drugs, seizures, debilitations, along the way. Until this last Monday. Luke had passed away, RIP. He isn’t suffering anymore, thankfully. He was a fighter thru and thru. 48yrs young. #fuckcancer you took my dear friend!!!
This is really just too awful.
The incredible Prof Richard Scolyer has just posted that the recurrence of glioblastoma has been significant and his prognosis is poor.
Such devastating news for the professor, his family and his close colleagues and friends.
He has, however, changed the world.
Thinking of Prof Richard Scolyer and hoping all he's facing sounds worse than it is.
#Glioblastoma #Cancer
https://www.dailymail.co.uk/news/article-14452423/Richard-Scolyer-brain-cancer.html
Daily Mail · Devastating health setback for former Australian of the Year fighting incurable cancer
Begging bowl time again. Later this month, on Sunday 23rd March, I’ll be running the Sheffield Half Marathon.
Looking to raise money for the University of Liverpool’s Glioblastoma research program, in memory of Mum.
If anyone would like to donate, just click on the link below.
#Running #SheffieldHalfMarathon #Glioblastoma
https://www.justgiving.com/page/nigel-kneale-5?utm_medium=FR&utm_source=CL
JustGivingNigel's fundraiser for University of LiverpoolHelp Nigel Kneale raise money to support University of Liverpool
A new collaborative research project in Turku, Copenhagen and Stockholm investigates the role of #cytomegalovirus in the development and progression of #glioblastoma. In Turku the study will be led by InFLAMES-PI Cecilia Söderberg-Nauclér.
@ki.se @biocityturku.bsky.social
bit.ly/4aVn6RC
https://bit.ly/4aVn6RC https://bsky.app/profile/inflames-flagship.bsky.social/post/3lhirlujiv22r #utu #yliopisto
InFLAMES Research Flagship · Joint Nordic brain cancer research project awarded €4M grant - InFLAMES Research FlagshipProfessor Cecilia Söderberg-Nauclér, InFLAMES group leader from the University of Turku in Finland, is investigating the links between human cytomegalovirus and brain tumours in a multi-million euro research project conducted in collaboration between researchers in Finland, Denmark, and Sweden. The Lundbeck Foundation has awarded a grant of approximately €4 million for the project. Söderberg-Nauclér applied […]
Glioblastoma, an aggressive and highly lethal cancer, produces cells that rapidly invade brain tissue, making it particularly difficult to treat. A new system for testing this cancerous cell invasion is an exciting breakthrough that may help discover new treatment options.
Lear more in this week's post: https://pennneuroknow.com/2025/01/28/fighting-brain-cancer-one-cell-at-a-time/
PennNeuroKnow · Fighting brain cancer, one cell at a timeGlioblastoma, an aggressive and highly lethal cancer, produces cells that rapidly invade brain tissue, making it particularly difficult to treat. A new system for testing this cancerous cell invasi…
Death, Grief, Cancer
Our @KalebicNereo group with our @francesco_i0ri0 Group identified ADD3 as a key gene driving #glioblastoma stem cell shape and tumour connectivity, uncovering growth and therapy resistance
Published in Life Science Alliance with support from AIRC
Human Technopole · Cancer stem cell morphology predicts glioblastoma growth and resistance - Human TechnopoleHuman Technopole researchers have identified adducin-γ (ADD3) as a crucial regulator of glioblastoma cancer stem cell morphology and intercellular bridges between tumour cells. These connections facilitate communication and allow tumour cells to share resources, evade chemotherapy, and survive in challenging conditions. The study has been funded by AIRC and the findings are published in Life Science Alliance.
DATE: November 13, 2024 at 08:00AM
SOURCE: BioWorld MedTech
Direct article link at end of text block below.
Quiescent, but not quiet, cancer stem cells in glioblastoma relapse
#medtech #stemcells #glioblastoma
Here are any URLs found in the article text:
Articles can be found by scrolling down the page at https://www.bioworld.com/topics/85-bioworld-medtech .
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t.coQuiescent, but not quiet, cancer stem cells in glioblastoma relapse
DATE: November 12, 2024 at 06:00PM
SOURCE: BioWorld MedTech
Direct article link at end of text block below.
Quiescent, but not quiet, cancer stem cells in glioblastoma relapse
#medtech #stemcells #glioblastoma
Here are any URLs found in the article text:
Articles can be found by scrolling down the page at https://www.bioworld.com/topics/85-bioworld-medtech .
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t.coQuiescent, but not quiet, cancer stem cells in glioblastoma relapse
DATE: October 02, 2024 at 08:00AM
SOURCE: BioWorld MedTech
Direct article link at end of text block below.
Elekta’s UNITED trial offers new glioma treatment option
#medtech @Elekta #glioma #braincancer #Electa #glioblastoma
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Articles can be found by scrolling down the page at https://www.bioworld.com/topics/85-bioworld-medtech .
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t.coElekta’s UNITED trial offers new glioma treatment option
DATE: October 01, 2024 at 06:00PM
SOURCE: BioWorld MedTech
Direct article link at end of text block below.
Elekta’s UNITED trial offers new glioma treatment option
#medtech @Elekta #glioma #braincancer #Electa #glioblastoma
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Articles can be found by scrolling down the page at https://www.bioworld.com/topics/85-bioworld-medtech .
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t.coElekta’s UNITED trial offers new glioma treatment option
Quantitative #GroundRounds at #MoffittCancerCenter with Kristin Swanson (Mayo Clinic) talking about sex differences in #Glioblastoma and ways to study it with #MathOnco and #machine_learning
Kristin is complementing her Machine Learning approach with knowledge that constraints the training of the network, something that makes a lot of sense since in clinical oncology there is not such thing as #BigData
My #GOP, #FoxNews-watching, #COVID-addled parents aren’t doing well.
My dad has had COVID twice and my mom three times (that we know of).
My dad has a #GBM #Glioblastoma and doesn’t have much time left.
My mom, who got over COVID two weeks ago, fell from a ladder at work yesterday hanging decorations and broke 3 ribs and has a compression fracture of T12.
Post-COVID falls and dizziness are a thing and no one can convince me that this didn’t factor into falling.
Stay safe out there.
Just going to put a question here to that had bothered me for the past two days, which I’m not sure if anyone would be able to answer:
For #Glioblastoma trial that uses the #mRANO criteria with neurological assessments done using #NANO prior to Survival Follow-up, is it common to then judge Clinical Status during Survival Follow-up of patient without #NANO?
And what is the rationale behind it?
#neurological #clinicaltrial #Glioblastoma
Today is Glioblastoma Awareness Day, which has the goal of educating people about the most common, complex, treatment-resistant and deadly type of brain cancer. Here's a story from MedicalNewsToday about a promising new treatment — an mRNA vaccine that could potentially retrain the body's immune system to attack and treat glioblastoma. A study on dogs with brain tumors published in the journal Cell earlier this year showed an increase in survival rates, and the scientists have now expanded their research to a small clinical trial on humans.
Medical News Today · New mRNA cancer vaccine helps immune system fight deadly brain tumors