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Ontario Outbreak InformationOutbreak: <a href="https://mstdn.ca/tags/Streptococcus" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Streptococcus</a> Pyogenes (<a href="https://mstdn.ca/tags/GAS" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#GAS</a> / <a href="https://mstdn.ca/tags/GroupAStrep" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#GroupAStrep</a>) Facility: Aspira Traditions of Durham Facility Type: Retirement Home Unit/Floor/Area: Third Floor, TCU Location: <a href="https://mstdn.ca/tags/Oshawa" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Oshawa</a> <a href="https://mstdn.ca/tags/Ontario" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Ontario</a> Date: 2025-03-17Public Health Unit: Durham Region Health Department Facility Tracking Hash: <a href="https://mstdn.ca/tags/DRHD0030" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#DRHD0030</a> PHU Tracking Hash: <a href="https://mstdn.ca/tags/OnObDRHD" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#OnObDRHD</a>Click or follow tracking hashtags to see data for individual facilities or a specific public health unit.

Auscandoc<a href="https://www.cbc.ca/news/canada/british-columbia/strep-a-infections-bc-children-1.7088496" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://www.cbc.ca/news/canada/british-columbia/strep-a-infections-bc-children-1.7088496</a> “B.C. health authorities are warning that group A strep was identified in four children who have died since mid-December, and the province is seeing unusually high levels of the disease this winter.” <a href="https://med-mastodon.com/tags/InvasiveGAS" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#InvasiveGAS</a> <a href="https://med-mastodon.com/tags/GAS" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#GAS</a> <a href="https://med-mastodon.com/tags/GroupAStrep" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#GroupAStrep</a> <a href="https://med-mastodon.com/tags/infectiousdiseases" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#infectiousdiseases</a>

Gabriele PollaraClear trends in hospital Group A strep admissions in UK. ⬇️ during and ⬆️ after <a href="https://med-mastodon.com/tags/COVID19" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#COVID19</a>. This is national Hospital Episode Statistics , which matches UKHSA data. Next question: what exactly drove the recent rise? Hospital admissions for group A streptococcal infections in England: current rates and historical perspective <a href="https://med-mastodon.com/tags/GAS" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#GAS</a> <a href="https://med-mastodon.com/tags/StrepA" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#StrepA</a> <a href="https://med-mastodon.com/tags/GroupAstrep" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#GroupAstrep</a> <a href="https://med-mastodon.com/tags/bacteria" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#bacteria</a> <a href="https://med-mastodon.com/tags/microbiology" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#microbiology</a> <a href="https://med-mastodon.com/tags/IDMastodon" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#IDMastodon</a> <a href="https://med-mastodon.com/tags/medicine" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#medicine</a> <a href="https://med-mastodon.com/tags/MedMastodon" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#MedMastodon</a> <a href="https://med-mastodon.com/tags/infectiousdiseases" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#infectiousdiseases</a> <a href="https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(23)00428-0/fulltext?dgcid=raven_jbs_aip_email" rel="nofollow noopener noreferrer" target="_blank">https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(23)00428-0/fulltext?dgcid=raven_jbs_aip_email</a>

Uli Schwarz-LinekAbout to finish <a href="https://mstdn.science/tags/PhD" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#PhD</a> in molecular microbiology/virology? Join us as <a href="https://mstdn.science/tags/postdoc" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#postdoc</a> at the BSRC in St Andrews and work with Michael Nevels and me to study mechanisms underlying the devastating synergy of <a href="https://mstdn.science/tags/GroupAStrep" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#GroupAStrep</a> and <a href="https://mstdn.science/tags/ChickenPox" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ChickenPox</a> co-infections. Full details: <a href="https://www.vacancies.st-andrews.ac.uk/Vacancies/W/4582/0/391937/889/research-fellow-ar2823mr" rel="nofollow noopener noreferrer" target="_blank">https://www.vacancies.st-andrews.ac.uk/Vacancies/W/4582/0/391937/889/research-fellow-ar2823mr</a>

Gabriele PollaraInfection with Streptococcus pyogenes after childbirth can have life threatening consequences. Here, Catton et al. show that the epidemiologically associated bacterial R28 protein targets the human CEACAM1 receptor to facilitate the pathogenesis of bacterial sepsis. <a href="https://med-mastodon.com/tags/GroupAstrep" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#GroupAstrep</a> <a href="https://med-mastodon.com/tags/StrepA" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#StrepA</a> <a href="https://med-mastodon.com/tags/science" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#science</a> <a href="https://med-mastodon.com/tags/MedMastodon" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#MedMastodon</a> <a href="https://med-mastodon.com/tags/IDMastodon" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#IDMastodon</a> <a href="https://med-mastodon.com/tags/immunology" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#immunology</a> <a href="https://med-mastodon.com/tags/academicchatter" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#academicchatter</a> <a href="https://www.nature.com/articles/s41467-023-37732-1#Sec9" rel="nofollow noopener noreferrer" target="_blank">https://www.nature.com/articles/s41467-023-37732-1#Sec9</a>

Gabriele PollaraInteresting to see drop in big spike in invasive Group A strep notifications in England.Big question is if there is going to be another peak now we enter the 'usual' season, or whether this was a solitary (big) early peak.<a href="https://med-mastodon.com/tags/IDMastodon" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#IDMastodon</a> <a href="https://med-mastodon.com/tags/MedMastodon" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#MedMastodon</a> <a href="https://med-mastodon.com/tags/GroupAstrep" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#GroupAstrep</a> <a href="https://med-mastodon.com/tags/GAS" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#GAS</a> <a href="https://med-mastodon.com/tags/iGAS" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#iGAS</a> <a href="https://med-mastodon.com/tags/bacteria" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#bacteria</a> <a href="https://med-mastodon.com/tags/microbiology" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#microbiology</a> <a href="https://www.gov.uk/government/publications/group-a-streptococcal-infections-activity-during-the-2022-to-2023-season/group-a-streptococcal-infections-10th-update-on-seasonal-activity-in-england" rel="nofollow noopener noreferrer" target="_blank">https://www.gov.uk/government/publications/group-a-streptococcal-infections-activity-during-the-2022-to-2023-season/group-a-streptococcal-infections-10th-update-on-seasonal-activity-in-england</a>

EMBO Mol. Medicine👉 Group A streptococci are experts at avoiding and disarming human antibodies with no available vaccines or antibody treatments. This study presents a novel interaction mechanism between antibodies & antigens that can induce protective immune function against group A streptococci. <a href="https://sciencemastodon.com/tags/StrepA" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#StrepA</a> <a href="https://sciencemastodon.com/tags/GroupAStrep" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#GroupAStrep</a> <a href="https://sciencemastodon.com/tags/immunefunction" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#immunefunction</a>By W. Bahnan, P. Nordenfelt & colleagues @LundsuniFull <a href="https://sciencemastodon.com/tags/openaccess" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#openaccess</a> article: <a href="https://doi.org/10.15252/emmm.202216208" rel="nofollow noopener noreferrer" target="_blank">https://doi.org/10.15252/emmm.202216208</a>See also: bit.ly/3HpORVH

IT NewsScarlet fever is soaring in UK after pandemic lull; invasive infections kill 8 - Enlarge / A microscope image of Streptococcus pyogenes, a common type o... - <a href="https://arstechnica.com/?p=1902735" rel="nofollow noopener noreferrer" target="_blank">https://arstechnica.com/?p=1902735</a> <a href="https://schleuss.online/tags/invasivegroupastrep" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#invasivegroupastrep</a> <a href="https://schleuss.online/tags/groupastreptococci" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#groupastreptococci</a> <a href="https://schleuss.online/tags/respiratoryviruses" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#respiratoryviruses</a> <a href="https://schleuss.online/tags/infectiousdisease" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#infectiousdisease</a> <a href="https://schleuss.online/tags/publichealth" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#publichealth</a> <a href="https://schleuss.online/tags/scarletfever" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#scarletfever</a> <a href="https://schleuss.online/tags/antibiotics" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#antibiotics</a> <a href="https://schleuss.online/tags/groupastrep" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#groupastrep</a> <a href="https://schleuss.online/tags/strepthroat" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#strepthroat</a> <a href="https://schleuss.online/tags/children" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#children</a> <a href="https://schleuss.online/tags/science" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#science</a> <a href="https://schleuss.online/tags/viruses" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#viruses</a> <a href="https://schleuss.online/tags/strepa" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#strepa</a> <a href="https://schleuss.online/tags/cdc" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#cdc</a> <a href="https://schleuss.online/tags/nhs" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#nhs</a> <a href="https://schleuss.online/tags/uk" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#uk</a>

Gabriele PollaraDespite platform issues, no reason to shun great content on <a href="https://med-mastodon.com/tags/twitter" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#twitter</a> Excellent thread on what we know re <a href="https://med-mastodon.com/tags/GroupAStrep" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#GroupAStrep</a> so far and papers published on how challenging it is to stop transmission <a href="https://med-mastodon.com/tags/IDMastadon" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#IDMastadon</a> <a href="https://med-mastodon.com/tags/MedMastodon" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#MedMastodon</a> <a href="https://med-mastodon.com/tags/microbiology" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#microbiology</a> <a href="https://twitter.com/Grampospath/status/1599408274264449028?s=20&t=LrxmC4Y89XdllaCXm6K6Cg" rel="nofollow noopener noreferrer" target="_blank">https://twitter.com/Grampospath/status/1599408274264449028?s=20&t=LrxmC4Y89XdllaCXm6K6Cg</a>

𝕵𝖆𝖒𝖎𝖊 🦠🔬💉<a href="https://mastodon.social/tags/groupAstrep" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#groupAstrep</a> <a href="https://mastodon.social/tags/%E9%8F%88%E7%90%83%E8%8F%8C" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#鏈球菌</a> <a href="https://mastodon.social/tags/kid" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#kid</a> <a href="https://mastodon.social/tags/UK" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#UK</a>英國已有4名孩童感染A型鏈球菌後身亡A型鏈球菌感染後可能出現喉嚨痛、發燒、輕微皮膚感染等症狀，少數案例可能會演變為重症導致死亡猩紅熱亦是由A型鏈球菌引起，初始症狀類似流感，之後起皮疹，舌頭呈現草莓舌態🔗：<a href="https://www.theguardian.com/science/2022/dec/02/fourth-child-dies-in-uk-after-contracting-step-a-infection" rel="nofollow noopener noreferrer" target="_blank">https://www.theguardian.com/science/2022/dec/02/fourth-child-dies-in-uk-after-contracting-step-a-infection</a>

Uli Schwarz-LinekVery sad to read news about a 6yo dying from invasive group A <a href="https://mstdn.science/tags/streptococcus" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#streptococcus</a> infection <a href="https://mstdn.science/tags/GroupAStrep" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#GroupAStrep</a>. Very important to be aware of symptoms.Ashford bacteria outbreak: Primary school pupil dies with infection<a href="https://www.bbc.co.uk/news/uk-england-surrey-63748975" rel="nofollow noopener noreferrer" target="_blank">https://www.bbc.co.uk/news/uk-england-surrey-63748975</a>

Uli Schwarz-LinekHi! <a href="https://mstdn.science/tags/introduction" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#introduction</a> to my <a href="https://mstdn.science/tags/science" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#science</a>:My group uses <a href="https://mstdn.science/tags/StructuralBiology" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#StructuralBiology</a> (<a href="https://mstdn.science/tags/NMR" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#NMR</a>, <a href="https://mstdn.science/tags/Crystallography" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Crystallography</a>, <a href="https://mstdn.science/tags/CryoEM" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#CryoEM</a>) and cell-based experiments to study protein interactions at the host:pathogen interface.We study how surface <a href="https://mstdn.science/tags/proteins" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#proteins</a> of Gram-positive bacteria, mainly TIE proteins (chemical harpoons) and M proteins of <a href="https://mstdn.science/tags/GroupAStrep" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#GroupAStrep</a>, interact with extracellular matrix and host cells.Our other interest is the <a href="https://mstdn.science/tags/RiftValleyFever" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#RiftValleyFever</a> phlebovirus NSs protein. Also dabble in protein engineering and tagging.

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