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#Epigenética

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Álvaro G. Molinero 👉 @KimeraGupta

✍️ BLOG | Esto era un caballero, una bacteria y un elemento móvil del genoma

"Lamarck ha dejado una profunda huella en la historia del pensamiento científico europeo. En este texto se analizan desde la genética y la biología molecular formas no darwinianas de herencia y que han jugado un relevante papel en la evolución de la vida y, en concreto, en la evolución de los mamíferos"

ENTRADA COMPLETA🔗 laquimeradegupta.tumblr.com/po

#TeoríaDeLaEvolución#Epigenética#Neolamarckismo
Michela

Si parla spesso di autismo come condizione genetica.
Ma oggi sappiamo che non è solo questione di geni.

L’epigenetica, l’ambiente, il sistema nervoso, il microbiota:
sono tutti pezzi del puzzle che raramente vengono raccontati insieme.

Buona domenica.
Grazie 🦔

#neurodivergenza #autismo #neuroscienze #epigenetica #consapevolezza  #michiyospace

michiyospace.altervista.org/la

LandEscape · La mia neurodivergenza non era tutta scritta nei geni. Era scritta anche nel mondo. E nessuno me l'ha mai detto - LandEscapeAnatomia di una consapevolezza negata Non sono arrivata a questa comprensione grazie a un medico, a una diagnosi tempestiva o a un percorso guidato. È stato un processo lungo, fatto di dubbi, letture, confronti e molte domande lasciate in sospeso. Ho cercato risposte in mancanza di alternative, e nel tempo ho iniziato a collegare elementi
Michela

Il corpo come archivio.
Denti, capelli, ossa: ciò che resta può raccontare tutto.

Ho scritto un articolo che mi ha portato a giorni di ricerche stimolanti.
Un viaggio tra scienza e indagini, dentro ciò che un tempo sembrava impossibile da leggere.
Oggi, invece, può parlare.

Grazie 🦔

#michiyospace
#neuroscienze  #scienzaforense #memoriadelcorpo #analisiDNA #criminologia  #tecnicheforensi  #epigenetica

michiyospace.altervista.org/sc

LandEscape · Scienza del crimine: come il nostro corpo rivela la verità - LandEscapeIl nostro corpo racconta storie.Non parla, ma conserva. Ogni capello, ogni dente, ogni traccia biologica è un indizio.Nella scienza forense, ciò che sembra banale può diventare decisivo: un frammento di tessuto, un’unghia, un capello spezzato.Oggi possiamo leggere nel corpo la geografia di una vita, la presenza di veleni, la durata di uno stress cronico, o
Nosoytunutri

¡Hola! Mi nombre es Lara, soy 🇦🇷
#presentación

Un día me di cuenta que soy un ser humano y eso me otorga una cualidad: LA PERMEABILIDAD. Desde entonces me dedico a divulgar sobre la relación que construimos (los ejemplares de humano) con el entorno.
¿Qué tienen que ver los poros, las metrópolis, el edificio en el que vivís, el campo mas cercano y el origen de las verduras que tenés en el cajón de la heladera?
Lo iremos desarrollando 🧚‍♀️✨️

#biología#epigenética#salud
Futuro Prossimo :verified:

Un semplice tampone può predire la velocità di invecchiamento e il rischio di mortalità. Un rivoluzionario biomarker epigenetici sviluppato negli USA supera i test del sangue in accuratezza. Il test analizza la metilazione del DNA nelle cellule della guancia, svelando i segreti del nostro orologio biologico. Voi fareste questo test? Sareste pronti a conoscere la vostra vera età biologica e il vostro rischio di mortalità?

#Biomarker #Epigenetica #salute #test

futuroprossimo.it/2024/10/biom

Manuel Cardeñosa 🍉

"Horvath y los suyos han examinado los patrones de metilación en 348 especies de mamíferos, incluida la del lector, y han hallado una fuerte asociación entre esos patrones y la vida máxima de cada especie."

La epigenética de la eterna juventud | Tendencias | Proyecto | EL PAÍS

elpais.com/proyecto-tendencias
#biología #genética #epigenética

El País · La epigenética de la eterna juventudLa vida media en los países occidentales se duplicó en el siglo XX de los 40 años a los ochenta, pero la vida máxima de nuestra especie es 122 años y no se ha movido de ahí
Continued thread
Fernando Valladares

Las respuestas epigenéticas y otros efectos transgeneracionales desempeñarán sin duda un papel importante en la adaptación al cambio climático y a otras alteraciones humanas de la biosfera, pero hace falta más investigación para comprobar su valor real en comparación con los cambios codificados en el ADN, es decir, por la herencia y la evolución “clásica”.

FUENTE:
royalsocietypublishing.org/doi

#epigenetica#adaptacion#crisis
Continued thread
Fernando Valladares

Se diferencian de las toxinas clásicas en varios aspectos, como el efecto a dosis bajas, la dosis no monotónica y los efectos transgeneracionales. Si los disruptores endocrinos son un mundo por investigar, sus efectos transngeneracionales apenas están comenzando a estudiarse.

FUENTE
frontiersin.org/articles/10.33

FrontiersEnvironmental Endocrine-Disrupting Chemical Exposure: Role in Non-Communicable DiseasesThe exponential growth of pollutant discharges into the environment due to increasing industrial and agricultural activities is a rising threat for human health and a biggest concern for environmental health globally. Several synthetic chemicals, categorized as potential environmental endocrine-disrupting chemicals (EDCs), are evident to affect the health of not only livestock and wildlife but also humankind. In recent years, human exposure to environmental EDCs has received increased awareness due to their association with altered human health as documented by several epidemiological and experimental studies. EDCs are associated with deleterious effects on male and female reproductive health; causes diabetes, obesity, metabolic disorders, thyroid homeostasis and increase the risk of hormone-sensitive cancers. Sewage effluents are a major source of several EDCs, which eventually reach large water bodies and potentially contaminate the drinking water supply. Similarly, water storage material such as different types of plastics also leaches out EDCs in drinking Water. Domestic wastewater containing pharmaceutical ingredients, metals, pesticides and personal care product additives also influences endocrine activity. These EDCs act via various receptors through a variety of known and unknown mechanisms including epigenetic modification. They differ from classic toxins in several ways such as low-dose effect, non-monotonic dose and trans-generational effects. This review aims t...
#epigenetica#disruptoresendocrinos#salud
Continued thread
Fernando Valladares

Pero también permiten identificar características epigenéticas que conduzcan a un aumento de la masa grasa en generaciones posteriores.

FUENTE
frontiersin.org/articles/10.33

#exposoma #epigenetica #ancestros #transgeneracional #descendencia

FrontiersInvestigating Possible Trans/Intergenerational Associations With Obesity in Young Adults Using an Exposome ApproachAnimal experiments demonstrate ways in which an exposure in one generation can be reflected in a variety of outcomes in later generations. In parallel human observational studies have shown associations between grandparental and parental exposures to cigarette smoking and/or nutrition and growth and survival of the grandchild. These studies have controlled for just a few confounders selected ad hoc. Here we use an exposome approach (using all available measures of exposure) to determine trans/inter-generational factors that may be important in studying environmental factors associated with fat mass in young human adults. The study takes advantage of the rich data available in the Avon Longitudinal Study of Parents and Children (ALSPAC). We test associations with features of grandparents (G0) and the childhood of the parents (G1) of 24-year olds (G2). We hypothesized that intergenerational associations would be revealed, particularly with exposure to cigarette smoke, and that these would vary with the sexes of all three generations. The study exposome analyzed 172 exposures to the maternal line and 182 to the paternal line. A series of stepwise regression analyses reduced the initial 40 unadjusted factors (P < 0.05) to eight independent features on the maternal line, and of 26 on the paternal line to five. We found strong associations between the father starting to smoke cigarettes regularly before age 11 and increased fat mass in his adult children (unadjusted = +7.82 [95%...
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