Fri, 18 Nov 2022 10:02:00 +0000
Science, RNA, FMRP, tumors, CD8TCells, CCL17, Tregs, IL33, M2, macrophages, PROS1, extracellularvesicles, cancerimmunology, rbp

In #Science (@sciencemagazine) this week, the Hanahan lab shows that the #RNA-binding protein #FMRP enables #tumors to evade being attacked by #CD8TCells. It does so by both suppressing #CCL17 & promoting #Tregs via #IL33 & #M2 #macrophages via #PROS1 & #ExtracellularVesicles!

https://bit.ly/Sci_abl7207

#CancerImmunology #RBP