Tue, 20 Dec 2022 16:17:59 +0000
myeloid, inflammatory, cytokines, dsRNA, sarscov2, misc, COVID19, children

Science Magazine (@sciencemagazine) First Release: Jean-Laurent Casanova & colleagues report that single-gene recessive inborn errors of OAS–RNase L pathway cause #myeloid cells to produce excess #inflammatory #cytokines following #dsRNA or #SARSCoV2 stimulation. This pathway may drive #MISC, a rare complication of #COVID19 in some #children!

https://bit.ly/Sci_abo3627