We had an amazing 42nd BSCB GenSoc UK Cilia Network e-symposium online today- back after a 7 month hiatus with 241-strong audience! However how do I hype the amazing #ECRs- students and postdocs- to a field that has not yet migrated here... We do this to 'grow' their networks but means me putting original content on Dilemmas.... #UKCilia2023 /1
It was a great session! We kick off with a masterclass in the first steps of #cilia membrane formation by Kerstin Schmidt from the Witzgall lab University of Regensburg, DE combining CLEM & STEM tomography for partial donuts in early ciliogenesis! #ukcilia2023 /2
Next up, modelling Joubert Syndrome in a dish- understanding poor genoptype-phenotype correlations in cerebral organoids for #ciliopathies! We marvelled at Melanie Eschment, Bachmann-Gagescu lab University of Zurich who dazzles us with neural phenotypes which differ in 2 and 3D! #ukcilia2023 /3
A Bachmann lab double header, next up was a phenomenal Masters project on unpicking molecular cascades underlying body-axis straightening in zebrafish, #ciliopathies & #scoliosis from Jacqueline Oberlin from Bachmann-Gagescu lab University of Zurich! #ukcilia2023 /4
Everyone’s favorite membrane-less organelles #Centriolarsatellites in #centrosome remodelling and #ciliogenesis- a paralogue in Drosophila opens the field to other model organisms. Great talk from Claudia Pachinger from the Dammermann Lab @ MaxvPerutzvLabs! #ukcilia2023 /5
Understanding #Bardet-Biedl renal phenotypes- human kidney disease in a dish for #ciliopathies- HipSci human healthy donors and rare disease, including 50 BBS patients- ambitious work from James Williams a PhD candidate
funded by BBS UK Charity in FIona Watt's lab at KCL! #ukcilia2023 /6
How #photoreceptors die in #retinitispigmentosa using #scRNAseq, proteomics & quantitative imaging with slow #RPGR & fast #PDE6B mouse models- understanding early and late disease mechanisms! Great talk by Fay Newton, postdoc extraordinaire funded by Fight for Sight UK in Megaw/Mill labs at MRC HGU, University of Edinburgh. #ukcilia2023 /7
Great discussion, great questions- thanks to all my speakers & our audience! Todays session was poster prize winners from EMBO Cilia 2022- more surprises next time! We will be back APRIL 18th 2023
for our second session #ukcilia2023- sign up here if you are not on my list! Free and open to all: https://eventbrite.co.uk/e/bscb-gensoc-uk-cilia-network-e-symposia-series-tickets-122092125835 /fin